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Pronunciation varies by accent · noun
(genetics) The insertion of a cDNA sequence at a particular locus in an organism's chromosome.
The advantage of this design is that the targeted knockin retains the intact endogenous aggrecan locus and expresses the tamoxifen-inducible CreERT2 protein from a second IRES-driven open reading frame.
Use knock in when its meaning, tone and grammar fit the full sentence. A synonym is not always a direct replacement.
Knock in means (genetics) The insertion of a cDNA sequence at a particular locus in an organism's chromosome.
The closest synonym depends on the sentence and intended sense.
The opposite depends on the specific sense.
The advantage of this design is that the targeted knockin retains the intact endogenous aggrecan locus and expresses the tamoxifen-inducible CreERT2 protein from a second IRES-driven open reading frame.
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